Matt Cain pitches perfect game for Giants (Video)

San Francisco Giants starter Matt Cain pitched the 22nd perfect game in major league history Wednesday night, including 14 strikeouts, during a 10-0 victory over the Houston Astros.

Cain got Astros pinch hitter Jason Castro to ground out to third base for the final out. Cain's 125-pitch outing was the first perfect game in Giants franchise history, which covers 130 years and includes time spent in New York.

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